Which statement best distinguishes apoptosis from necrosis in neurons under injury, including the roles of calcium and mitochondria?

• A. Apoptosis is rapid lysis; necrosis is programmed with caspases.
• B. Necrosis is energy-dependent; apoptosis is passive.
• C. Apoptosis is programmed, energy-dependent, involves caspases; necrosis is uncontrolled and often due to severe injury.
• D. Mitochondria do not play a role in either process.

Answer: (C)